Regenerative Medicine

Regenerative Medicine is a major medical advancement that supports the body so that it can restore itself. It helps the body reduce inflammation and replace or regenerate tissue that has been damaged by age, disease or trauma.

Through exosomes, stem cells and peptides, we treat conditions affecting the foot, ankle, and lower leg to support healing, improve mobility, and reduce discomfort over time. These healing mediators are injected directly into the damaged areas by our Podiatrist to drive better outcomes.

This innovative therapy is our best tool to delay surgery or keep patients out of the operating room all together.

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Peptides

Exosomes

Hyaluronic Acid

Peptides are short chains of amino acids which are the building blocks of proteins within our bodies. They are vital for several biological processes, such as immune response, inflammation control, and tissue repair.

Because peptides can directly address soft tissue injuries, inflammation, and degenerative changes, they are useful for those with foot, ankle and lower leg issues. Peptides address core problems rather than just masking symptoms like typical medications do. This results in long-term benefits without major negative effects.

Peptides

PDA is a highly stable and bioavailable form of BPC 157. It helps support the body’s natural healing processes by promoting tissue repair, reducing inflammation and increasing blood flow. The growing body of literature supports this! A paper from 2024, a systematic review covering 36 studies, found BPC-157 improved outcomes across muscle, tendon, ligament, and bone injury models, with 7 of 12 people reporting chronic pain relief lasting more than six months after a single treatment.

PDA works through the following mechanisms of action:

Promotes angiogenesis by upregulating VEGF
Enhances tissue perfusion and reduces thrombosis by modulating the Nitric Oxide system
Reduces inflammation by reducing pro-inflammatory cytokines expression
Demonstrates cytoprotective effects against oxidative stress
Stimulates fibroblast migration and collagen synthesis

This peptide is helping people who suffer from chronic inflammation and pain due to:

Plantar fasciitis
Tendonitis or tendon ruptures
Ligament tears/sprains
Arthritis
Surgery

PDA (Pentadecapeptide arginate)

PDA pricing and Administration
$450 per month

PDA injections are administered once per month in the office, directly into the injured/damaged site. In between those visits, the patient will administer their own injections subcutaneously, every day. A treatment course of 2 to 3 months is recommended for PDA. Patients typically start to feel results after 4-8 weeks.

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Exosomes

exosomes pricing and Administration
$5,850

Exosomes are administered one time, in the office, directly into the injured/damaged site. There are no follow up injections done by the patient at home. Patients typically start to feel results after 3-4 months.

Exosomes are tiny extracellular vesicles that deliver bioactive molecules to tissues. This includes:

Proteins and enzymes for tissue remodeling
mRNA to alter gene expression toward regeneration
miRNA to regulate inflammation and cellular repair
Growth factors (VEGF, TGF-B) which to encourage vascularization and healing.

While traditional injections often focus on short term symptom reduction, exosome therapy is aimed at influencing cellular signaling, inflammation, and tissue repair pathways. The goal is to support the biological environment that affects recovery rather than temporarily masking discomfort. In fact, exosomes have shown comparable or superior therapeutic efficacy compared to stem cells alone. They exhibit lower immunogenicity and present an enhanced safety profile by avoiding concerns related to uncontrolled differentiation and tumorigenicity associated with live cells (stem cells).

Research shows particular promise for the following issues:

Osteoarthritis: Intra-articular exosome injections have demonstrated cartilage regeneration potential and pain reduction in preclinical models, with early human data emerging.
Tendon and ligament healing: Exosome delivery to injured tendons accelerates organized collagen deposition and reduces fibrotic scarring in animal models.
Muscle repair: Exosomal signals promote satellite cell activation (the resident stem cells responsible for skeletal muscle regeneration) after crush injury or overuse damage.
Wound Healing: Studies show exosomes stimulate cellular repair programs, accelerating wound closure and reducing scar formation.

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Exosomes and Peptide combination

Exosomes and peptides work synergistically and are often used together to supercharge healing. While exosomes deliver bioactive molecules that can reprogram cellular behavior and fine-tune the healing environment, peptides bring precise, receptor-targeted signaling that can amplify specific repair processes. The two are used together with the aim of creating an environment more conducive to healing to reduce pain and get patients back on their feet fast.

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Hyaluronic acid

Hyaluronic Acid Pricing and Administration
$800

Hyaluronic acid injections are administered in the office, directly into the injured/damaged site. There are no follow up injections done by the patient at home. Most patient require a total of 3-5 HA injections, spaced out once per week and start feeling the benefits after 3-4 months.

Patients with allergies to hyaluronan products, cinnamon, or products from birds such as feathers, eggs, and poultry should avoid this type of injection.

Hyaluronic Acid does not technically fall under the regenerative medicine category but it is included here for it’s ability to help patients delay or avoid surgery. It is an important, naturally occurring component of the synovial fluid found in joints.

Arthritis can cause the degradation of hyaluronic acid which has been associated with vulnerability of cartilage, pain and joint stiffness. Hyaluronic acid injections may reduce inflammation, lubricate the joint, act as a shock absorber and even stimulate the body’s production of this substance to improve pain and function.

This procedure is done in the office. Hyaluronic Acid, derived from rooster combs, is injected into the painful joint.

While results vary, many patients experience long-term improvement in both pain and function. It is a great option for patients with painful ankle or great toe joint arthritis, looking to delay or avoid surgery or to avoid taking narcotic pain medication.

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what to expect from injections

Patients will be able to drive to and from their appointments. Patients should avoid straining their joint/tissues where the injection was administered and should avoid strenuous activities and prolonged standing for a few days after the injection.

Mild injection site pain and swelling are the most common side effects. Please speak with the Podiatrist regarding additional potential side effects for specific injections.

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Frequently Asked Questions

Joint pain, arthritis, tendon and ligament injuries, sports injuries, plantar fasciitis, chronic pain conditions, certain nerve conditions.
Peptides are considered very well tolerated, however, there a paucity of long-term safety data. Injection site reactions are possible, as with any injection. Evidence concerning drug-peptide interactions is largely unavailable. Heightened caution is recommended when considering these compounds in patients receiving anticoagulant or antiplatelet therapy, given their possible influence on hemostasis and wound-healing dynamics. Likewise, individuals undergoing immunosuppressive treatment warrant careful assessment due to potential modulation of immune system activity and tissue repair mechanisms. Most critically, patients with active malignancies or significant cancer risk factors may not be appropriate candidates due to the potential for promoting tumor growth and metastasis through angiogenesis stimulation. Pregnancy and lactation represent additional contraindications due to the absence of safety data in these populations. Patients with severe hepatic or renal impairment may require special consideration, though specific dosing guidelines for these populations have not been established. Similarly, patients with bleeding disorders or those at high risk for bleeding complications may require careful evaluation before initiating peptide therapy.
Exosomes are considered a more ethical alternative to traditional stem cell therapies because they do not contain living cells, eliminating major moral concerns. By utilizing non-living nanoparticles, therapies avoid the destruction of embryos, genetic manipulation controversies, and tumor risks associated with living cell transplants.
Cord blood (plasma derived).
Certain components, such as PRP preparation systems, are FDA-cleared. However, many regenerative therapies are still considered investigational. We adhere to current FDA guidelines and offer only those treatments that are compliant with ethical and legal standards.
While traditional medicine often focuses on managing symptoms, regenerative medicine aims to address the root cause of injury or disease by stimulating the body’s natural ability to heal and regenerate tissue.
Most regenerative treatments are minimally invasive and generally well-tolerated. While mild discomfort during the injection is normal, local anesthesia can be used to maximize comfort.
Results vary depending on the individual and the condition being treated. Most patients start to notice improvements within 4 to 12 weeks, with continued progress over several months.
The number of treatments required depends on your specific condition, overall health, and response to therapy. Some individuals see results from a single session, while others may require a series of treatments spaced several weeks apart. Your physician will discuss a personalized plan during your consultation.
Certain components, such as PRP preparation systems, are FDA-cleared. However, many regenerative therapies are still considered investigational. We adhere to current FDA guidelines and offer only those treatments that are compliant with ethical and legal standards.
Ideal candidates include individuals with musculoskeletal injuries or chronic conditions who have not responded well to conservative treatments like physical therapy or medications. Regenerative therapies are also suitable for patients seeking to accelerate recovery from both surgical and non-surgical conditions. A meeting with your doctor is necessary to determine eligibility.
Yes. Regenerative treatments can be safely administered after surgery and may aid in recovery by promoting tissue healing and reducing inflammation.
Absolutely. Regenerative therapies can be used in conjunction with surgical procedures to enhance outcomes and support faster recovery. This is determined on a case-by-case basis with your physician.
Recovery is typically minimal. Most patients can return to daily activities shortly after treatment, though high-impact or strenuous activity may need to be limited for a few weeks depending on the procedure.
There are generally no strict restrictions. However, your provider will give you specific post-treatment guidelines tailored to your condition to optimize healing and outcomes.
There is no specific age limit. Candidacy is based on individual health status, not age. Our team will evaluate your overall health and medical history to determine if regenerative therapy is appropriate for you.
There is no specific age limit. Candidacy is based on individual health status, not age. Our team will evaluate your overall health and medical history to determine if regenerative therapy is appropriate for you.
Yes, you can use your HSA or FSA card to pay for treatments. Regenerative therapies typically qualify as eligible medical expenses under most plans. Please check with your plan administrator for confirmation.
Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing
Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review
BPC-157 and TB-500: Background, Indications, Efficacy, and Safety
The potential of exosomes in regenerative medicine and in the diagnosis and therapies of neurodegenerative diseases and cancer
Exosome-based strategy for degenerative disease in orthopedics: Recent progress and perspectives