Regenerative Medicine
Another Option for Chronic Foot and Ankle Pain
If you're living with chronic foot or ankle pain and haven't found relief with traditional treatments, regenerative medicine may be an option worth discussing.
At Renew Foot & Ankle Wellness Center, we believe every patient deserves an individualized treatment plan. Depending on your diagnosis, overall health, and treatment goals, regenerative therapies may be considered as part of a comprehensive approach to care.
Our goal is to help you understand all available treatment options so you can make an informed decision that's right for you.
WHAT IS REGENERATIVE MEDICINE
Regenerative medicine is an evolving area of medicine focused on supporting the body's natural healing processes.
Rather than simply addressing symptoms, regenerative therapies are being studied for their potential role in supporting tissue repair and recovery in certain musculoskeletal conditions.
Although research continues to develop, regenerative medicine is not appropriate for every patient or every condition. During your consultation, Dr. Shannon Carmignani will review your diagnosis, discuss available treatment options, and determine whether regenerative therapies may be appropriate for your individual situation.
CONDITIONS THAT MY BE EVALUATED
Depending on your diagnosis, regenerative therapies may be considered as part of your treatment plan for conditions such as:
Plantar fasciitis
Achilles tendinopathy
Posterior tibial tendon dysfunction
Peroneal tendon injuries
Ankle arthritis
Great toe arthritis
Chronic tendon injuries
Ligament injuries
Certain overuse injuries
Treatment recommendations are individualized and based on your examination, imaging findings, medical history, and treatment goals.
OUR TREATMENT APPROACH
Every patient begins with a comprehensive evaluation.
Your treatment plan may include one or more options, including activity modifications, shoe gear modifications, bracing, taping, orthotics, physical therapy, injection therapies, regenerative medicine and or surgical treatment when appropriate.
Our philosophy is to recommend the least invasive treatment that aligns with your condition and goals whenever possible.
REGENERATIVE TREATMENT OPTIONS
Depending on your individual needs, treatment options may include regenerative therapies that are discussed during your consultation.
These therapies are intended to support your body's natural healing processes and may be considered for select patients after a careful evaluation.
Potential goals of treatment may include:
Reducing inflammation
Supporting tissue repair
Improving function
Reducing pain
Helping patients return to desired activities
Individual results vary, and no specific outcome can be guaranteed. It is also important to understand that some regenerative therapies, such as compounded peptides and exosomes, are not FDA approved which means safety and efficacy have not been established by federal clinical trials.
WHAT TO EXPECT
If regenerative treatment is recommended in the form of injection, your procedure is performed in the office.
Following injections:
Most patients are able to drive themselves home.
Temporary soreness at the injection site may occur.
Activity modifications may be recommended for several days.
Recovery timelines vary depending on the condition being treated and the specific therapy used.
We'll provide detailed post-treatment instructions based on your individual care plan.
Frequently Asked Questions
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No. Not every patient or every condition is an appropriate candidate for regenerative medicine. A consultation is necessary to determine whether these treatments may be appropriate for your situation.
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Some regenerative therapies used in clinical practice involve products that are not approved by the FDA for orthopedic or musculoskeletal indications.
During your consultation, we'll discuss the regulatory status of any recommended treatment, along with its potential benefits, risks, and limitations.
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While traditional medicine often focuses on managing symptoms, regenerative medicine aims to address the root cause of injury or disease by stimulating the body’s natural ability to heal and regenerate tissue.
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The best way to determine whether regenerative medicine may be appropriate is through a comprehensive evaluation with Dr. Carmignani.
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There are generally no strict restrictions. However, your provider will give you specific post-treatment guidelines tailored to your condition to optimize healing and outcomes.
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Certain compounded peptides and exosome products are not approved by the FDA. Safety and effectiveness have not been established through FDA approval for many orthopedic or musculoskeletal uses.
If these therapies are discussed during your consultation, we'll review the available evidence, known risks, uncertainties, and alternative treatment options.
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Recovery varies depending on your diagnosis, the treatment performed, and your overall health. We'll discuss what to expect based on your individualized treatment plan.
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Many regenerative therapies are considered elective and are not covered by insurance. We'll review expected costs before treatment so you can make an informed decision.
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Many patients can use their HSA or FSA card to pay for treatments. Please check with your plan administrator for confirmation.
Additional REading
Research into regenerative medicine continues to evolve. Patients interested in learning more may find the following peer-reviewed publications helpful. These articles are provided for educational purposes and should not be interpreted as evidence that any specific treatment is appropriate for an individual patient or that similar results can be expected.
Regeneration or Risk. A Narrative Review of BPC-157 for Musculoskeletal Healing (2025).
From Regeneration to Analgesia: The Role of BPC-157 in Tissue Repair and Pain Management (2026)
Exosome-Based Strategy for Degenerative Disease in Orthopedics (2022)